產(chǎn)品概述

Specificity ：The product is specific for human CD3.

Host Species： Mouse

Immunogen ：Recombinant human CD3

Species Reactivity ：Human

Conjugate： Unconjugated

應(yīng)用指導(dǎo)

Working concentrations for specific applications should be determined by the investigators. The suitability of this antibody for applications other than those listed below has not been determined. For flow cytometric staining, the following concentration range is recommended starting points for this product and is suggested that the reagent be titrated for optimal performance for each application.

Application：Flow Cytometry

Recommended Usage：≤ 0.25 µg per million cells in 100 µl volume. It is strongly recommended that the reagent should be titrated for optimal performance for each application.

產(chǎn)品屬性

Form ：Liquid

Storage Buffer： Supplied in 10 mM Sodium Citrate, 150 mM NaCl, 0.02 mg/ml Polysorbate 80, pH 5.0.

Concentration： 1 mg/ml

Endotoxin Level： < 0.5 EU/μg by gel clotting method

Storage Instructions ：The product remains stable up to 12 months at 4 °C from date of receipt. For longer time storage, store at -80 °C. Avoid repeated freeze-thaw cycles.

Purification ：Protein A affinity column

Isotype： Mouse IgG2a

Clonality： Monoclonal

Note ：GenScript can customize this product per customer's request including conjugations, product size, buffer components, etc.

技術(shù)背景

Target Background ：CD3 is a member of the immunoglobulin superfamily, expressed on T cells. It is composed of four distinct chains (ε, γ, δ, ζ). CD3 antigen can form a complex with the T cell receptor (TCR) to generate an activation signal in T cells, which plays an important role in TCR signal transduction and both cytotoxic T cell ( CD8 + na?ve T cells) and T helper cells (CD4+ na?ve T cells) activation.

Synonyms： CD3; cluster of differentiation 3

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.