產(chǎn)品概述

Specificity： The product is specific for human CD28.

Host Species ：Mouse

Immunogen： Recombinant human CD28

Species Reactivity： Human

Conjugate： Unconjugated

應(yīng)用指導(dǎo)

Working concentrations for specific applications should be determined by the investigators. The suitability of this antibody for applications other than those listed below has not been determined. For flow cytometric staining, the following concentration range is recommended starting points for this product and is suggested that the reagent be titrated for optimal performance for each application.

Application：Recommended Usage

Flow Cytometry： ≤ 2 μg per million cells in 100 μl volume. It is strongly recommended that the reagent should be titrated for optimal performance for each application.

產(chǎn)品屬性

Form ：Liquid

Storage Buffer： Supplied in 10 mM Sodium Citrate, 150 mM NaCl, pH 6.5.

Concentration ：1 mg/ml

Endotoxin Level： < 0.5 EU/μg by gel clotting method

Storage Instructions ：The product remains stable up to 12 months at 4 °C from date of receipt. For longer time storage, store at -80 °C. Avoid repeated freeze-thaw cycles.

Purification ：Protein A affinity column

Isotype： Mouse IgG1κ

Clonality： Monoclonal

Note： GenScript can customize this product per customer's request including conjugations, product size, buffer components, etc.

技術(shù)背景

Target Background ：CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. It plays an important role in cell proliferation and cytokine production and promotion of T-cell survival. It also enhances the production of IL-4 and IL-10 in T cells in conjunction with TCR/CD3 ligation and CD40L co-stimulation.

Synonyms： CD28; TP44; T-cell-specific surface glycoprotein CD28; Cluster of differentiation 28

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.